Renal Sympathetic Denervation and Daily Life Blood Pressure in Resistant Hypertension: Simplicity or Complexity? Running title: Parati et al.; 24h blood pressure and renal denervation
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Is isolated systolic hypertension an indication for renal denervation?
Ewen et al. recently reported in the journal Hypertension that they investigated, for the first time, the effect of renal denervation on blood pressure in 63 patients with isolated systolic hypertension (Ewen et al., 2014). The authors concluded that renal denervation reduced office and ambulatory blood pressure in patients with isolated systolic hypertension (Ewen et al., 2014). However, this ...
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Animal and human studies have demonstrated that chronic activation of renal sympathetic nerves is critical in the pathogenesis and perpetuation of treatment-resistant hypertension. Bilateral renal denervation has emerged as a safe and effective, non-pharmacological treatment for resistant hypertension that involves the selective ablation of efferent and afferent renal nerves to lower blood pres...
متن کاملElectric nerve stimulation to monitor the efficacy of renal denervation.
1 reported a substantial blood pressure decrease (−27/17 mm Hg at 12 months) after percutaneous radiofrequency catheter-based renal sympathetic denervation in a cohort of 45 patients with resistant hypertension. One year later, the results of this proof-of-concept study were confirmed in 106 resistant hypertensive patients randomized 1:1 to renal denervation plus previous drug treatment versus ...
متن کاملLetter by Wang regarding article, "renal denervation for the treatment of cardiovascular high risk-hypertension or beyond?".
Letter by Wang Regarding Article, “Renal Denervation for the Treatment of Cardiovascular High Risk-Hypertension or Beyond?” To the Editor: In their article titled “Renal denervation for the treatment of cardiovascular high risk-hypertension or beyond?” Böhm et al presented an excellent overview on renal denervation and its clinical indications. The authors emphasized the blood pressure– lowerin...
متن کاملRenal denervation for the treatment of cardiovascular high risk-hypertension or beyond?
Hypertension imposes a major burden of morbidity and mortality and is associated with sympathetic nervous system overactivity. Renal sympathetic denervation has been shown to reduce office blood pressure, ambulatory blood pressure, and sympathetic activity in patients with resistant hypertension. Therefore, the procedure has attracted a lot of attention. Beyond blood pressure, renal denervation...
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